Nixon Lab Research Covered in Nature

“The future of Alzheimer’s treatment,” an Outlook piece recently published online in Nature, discusses the welcome arrival of drugs that clear away brain plaques but cautions that targeting amyloid alone might not be enough to halt the disease. The article highlights the alternative theory, pioneered by Dr. Ralph Nixon and his lab in NKI’s Center for Dementia Research, that there is an even earlier target for Alzheimer’s intervention: dysfunction of lysosomes, the cells’ waste-clearance machinery. Dr. Nixon’s theory is gaining increasing acceptance in the research community.