Investigators Receive Funding to Probe Genetic Protection in Alzheimer’s

Efrat Levy, PhD, Paul Mathews, PhD (Center for Dementia Research), and Donald Wilson, PhD (Emotional Brain Institute) are Co-Principal Investigators on a large RF1 NIA grant titled “Neuronal protective apolipoprotein E2-mediated endocytic and exocytic pathways”. This application was in response to a request for applications from the NIA designed to fill in the significant gap in the field’s understanding of why the apolipoprotein E2 allele is protective against Alzheimer’s disease. The success of this grant was made possible by preliminary findings by Kathy Peng during her graduate studies, by the efforts of Brett East and Gloria Fleming, and through NKI’s mouse resources, supported in part by the efforts of Monika Pawlik and by Kathleen Shannon and the rest of the facility staff.