Sandeep Malampati, Ph.D.

Sandeep Malampati received his bachelor’s degree in pharmacy and master’s degree in pharmacology from The Tamilnadu Dr. M.G.R. Medical University in Chennai, India. Before starting to work in Hong Kong, he was employed in the drug discovery research wing of Orchid Chemicals & Pharmaceuticals Limited. Then, at Hong Kong Baptist University, he investigated the efficacy of medicinal compounds for their ability to induce proteasomal and autophagic degradation of different pathological proteins like α-synuclein, amyloid beta, and hyperphosphorylated tau. For his Ph.D. in Neuroscience – Translational Medicine (supervised by Prof. Li Min, Prof. Zhang Ge and Dr. Song Juxian), Sandeep examined the efficacy of a small molecule TFEB activator in Alzheimer’s disease (AD) experimental models for the autophagic clearance of AD pathological proteins and also for restoring the behavioral impairment observed in AD. Sandeep joined Dr. Ralph Nixon’s lab as a postdoctoral fellow in October, 2020.