Jay Nierenberg, M.D., Ph.D.

Jay Nierenberg, M.D., Ph.D.

Research Scientist
Clinical Research

Initially a basic scientist, Dr. Nierenberg completed his undergraduate studies in Behavioral Biology at The Johns Hopkins University where he was a recipient of a Leidy Foundation Scholarship. There he conducted behavioral pharmacology research at the Johns Hopkins School of Medicine, after which he worked at the National Institutes of Health for two years doing research on kindling-related neural plasticity. He received M.D. and Ph.D. (in Neurobiology and Anatomy) degrees from the University of Rochester School of Medicine and Dentistry under a National Research Service Award from the National Institute of Mental Health. After completing medical school, he attended the University of Pennsylvania for Psychiatry internship and completed Psychiatry Residency at Harvard Medical School, where he received a DuPont Warren Fellowship to carry out research in first episode schizophrenia. In 2001, Dr. Nierenberg came to the Nathan Kline Institute and to New York University, where he completed a Clinical Research Fellowship in Psychiatry. While at NKI, he has received multiple grant awards as Principal Investigator and has collaborated on numerous research projects focusing on substance abuse, disorders of the aging, and schizophrenia. He has spoken at multiple international scientific meetings, actively reviews manuscripts for numerous medical journals, and has reviewed grants for multiple NIH Special Emphasis study groups as well as the Alzheimer’s Association.

  • “Future Leaders in Psychiatry” Travel Award, Emory School of Medicine and Janssen Pharmaceuticals
  • Young Investigator Award, International Congress on Schizophrenia Research
  • American College of Neuropsychopharmacology (ACNP) Young Investigator Memorial Travel Award
  • R01 Research Project Grant, “Longitudinal Brain Recovery Following Abstinence from Cocaine” (R01 DA021305)

Select Publications

  • Nierenberg J, Salisbury DF, Levitt JJ, David EA, McCarley RW, Shenton ME. Reduced left angular gyrus volume in first-episode schizophrenia. Am J Psychiatry. 2005 Aug;162(8):1539-41. doi: 10.1176/appi.ajp.162.8.1539. PMID: 16055780; PMCID: PMC2766930.
  • Hoptman MJ, Ardekani BA, Butler PD, Nierenberg J, Javitt DC, Lim KO. DTI and impulsivity in schizophrenia: a first voxelwise correlational analysis. Neuroreport. 2004 Nov 15;15(16):2467-70. doi: 10.1097/00001756-200411150-00007. PMID: 15538176; PMCID: PMC1550497.
  • Li X, Branch CA, Nierenberg J, Delisi LE. Disturbed functional connectivity of cortical activation during semantic discrimination in patients with schizophrenia and subjects at genetic high-risk. Brain Imaging Behav. 2010 Mar;4(1):109-20. doi: 10.1007/s11682-010-9090-3. Epub 2010 Feb 17. PMID: 20503118.
  • Hoptman MJ, Nierenberg J, Bertisch HC, Catalano D, Ardekani BA, Branch CA, Delisi LE. A DTI study of white matter microstructure in individuals at high genetic risk for schizophrenia. Schizophr Res. 2008 Dec;106(2-3):115-24. doi: 10.1016/j.schres.2008.07.023. Epub 2008 Sep 20. PMID: 18804959.
  • Butler PD, Hoptman MJ, Nierenberg J, Foxe JJ, Javitt DC, Lim KO. Visual white matter integrity in schizophrenia. Am J Psychiatry. 2006 Nov;163(11):2011-3. doi: 10.1176/ajp.2006.163.11.2011. PMID: 17074957; PMCID: PMC1975779.
  • Ardekani BA, Nierenberg J, Hoptman MJ, Javitt DC, Lim KO. MRI study of white matter diffusion anisotropy in schizophrenia. Neuroreport. 2003 Nov 14;14(16):2025-9. doi: 10.1097/00001756-200311140-00004. PMID: 14600491.