Search
Mr. Bare utilizes the fundamental concepts of flow cytometry in the detection, characterization, and separation of biological particles at both the cellular and subcellular domains. His research interests involve the development and refinement of commercial cell sorting instruments for fluorescent-tagged studies of extracellular vesicle (EV) populations in both normal and pathologic human cohorts. In addition, Mr. Bare is involved in the development of mechanisms to characterize and separate extracellular vesicles using label-free optical spectroscopy and multi-illumination spectral signature detection with potential for therapeutic applications. His research has taken two paths. The first is to assess EV diversity and signatures on current multilaser cytometers. The second is to develop detection hardware specific to the extracellular vesicle size range and coordinate physical phenomena such as Brillouin light scatter and the x-ray water window.