SearchFor more information, please visit our lab website (shuolab.github.io).
We are currently recruiting at all levels (postdocs, PhD students, Master’s students, and undergraduate researchers). If you are interested, please email your CV to the PI ([email protected]).
Some of life’s most cherished moments, like stepping onto a college campus for the first time or seeing a loved one after a long time apart, can remain etched into our memories for a lifetime. But where, exactly, do memories — from defining life episodes to our impressions about people — reside in the brain? This remains one of neuroscience’s great mysteries. We are driven by such long-standing questions as:
- How do neural networks encode and store episodic and semantic information?
- How is stored information retrieved and utilized to support cognitive processes like thinking and planning?
- What molecules underpin memory processes, specially those involved in memory storage?
- How can we restore memory processes in disorders such as Alzheimer’s disease?
Research in our lab focuses on elucidating how memory is encoded, retained, and retrieved within neural networks and molecules in the brain. We employ and develop cutting-edge tools to record and manipulate neuronal and molecular activities to unravel neural mechanisms underlying memory processes. Our integrative approach combines electrophysiology, imaging, behavior, genetic manipulations, omics, and computational modeling.
The major tools used in the lab include in vivo electrophysiology, two-photon calcium imaging, one-photon endoscopic imaging, fiber photometry, opto-/chemo-genetic manipulations, and ex vivo electrophysiology. We also actively develop our own tools to address specific scientific questions through bioengineering, chemical synthesis, (nano)materials engineering, and electrical engineering.
