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The Nathan S. Kline Institute for Psychiatric Research

Jay Nierenberg, M.D., Ph.D.

Jay Nierenberg, M.D., Ph.D.

Research Scientist
Center for Biomedical Imaging and Neuromodulation

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Initially a basic scientist, Dr. Nierenberg completed his undergraduate studies in Behavioral Biology at The Johns Hopkins University where he was a recipient of a Leidy Foundation Scholarship. There he conducted behavioral pharmacology research at the Johns Hopkins School of Medicine, after which he worked at the National Institutes of Health for two years doing research on kindling-related neural plasticity. He received M.D. and Ph.D. (in Neurobiology and Anatomy) degrees from the University of Rochester School of Medicine and Dentistry under a National Research Service Award from the National Institute of Mental Health. After completing medical school, he attended the University of Pennsylvania for Psychiatry internship and completed Psychiatry Residency at Harvard Medical School, where he received a DuPont Warren Fellowship to carry out research in first episode schizophrenia. In 2001, Dr. Nierenberg came to the Nathan Kline Institute and to New York University, where he completed a Clinical Research Fellowship in Psychiatry. While at NKI, he has received multiple grant awards as Principal Investigator and has collaborated on numerous research projects focusing on substance abuse, disorders of the aging, and schizophrenia. He has spoken at multiple international scientific meetings, actively reviews manuscripts for numerous medical journals, and has reviewed grants for multiple NIH Special Emphasis study groups as well as the Alzheimer’s Association.

  • “Future Leaders in Psychiatry” Travel Award, Emory School of Medicine and Janssen Pharmaceuticals
  • Young Investigator Award, International Congress on Schizophrenia Research
  • American College of Neuropsychopharmacology (ACNP) Young Investigator Memorial Travel Award
  • R01 Research Project Grant, “Longitudinal Brain Recovery Following Abstinence from Cocaine” (R01 DA021305)
Select Publications

Nierenberg J, Salisbury DF, Levitt JJ, David EA, McCarley RW, Shenton, ME.  Reduced left angular gyrus volume in first episode schizophrenia.  American Journal of Psychiatry. 2005 162:1539-41.

Nierenberg J, Pomara N, Hoptman MJ, Sidtis JJ, Ardekani BA, Lim KO.  Abnormal white matter integrity in healthy APOE Ɛ4 carriers.  NeuroReport. 2005 16:1369-72.

Bell, RP, Foxe JJ , Nierenberg J, Hoptman MJ, Garavan H.  Assessing white matter integrity as a function of abstinence duration in former cocaine-dependent individuals.  Journal of Drug and Alcohol Dependence. 2011 114, 159-168.

Connolly CG, Foxe JJ, Nierenberg J, Shpaner M, Garavan H.  The neurobiology of cognitive control in successful cocaine abstinence.  Drug and Alcohol Dependence. 2012 121:45-53. 

Hashimoto K, Bruno D, Nierenberg J, Marmar CR, Zetterberg H, Blennow K, Pomara N. Abnormality in glutamine-glutamate cycle in the cerebrospinal fluid of cognitively intact elderly individuals with major depressive disorder: a 3-year follow-up study. Transl Psychiatry. 2016 Mar 1;6:e744.