Dr. Guilfoyle has worked in the NMR field for over 30 years and has spent the last 18 years using MR methods in the study of neuropsychiatric disease. He has developed methods for high speed imaging suitable for rodent fMRI and fMRS experiments.
Baslow MH, Cain CK, Sears R, Wilson DA, Bachman A, Gerum S, Guilfoyle DN. Stimulation-induced transient changes in neuronal activity, blood flow and N-acetylaspartate content in rat prefrontal cortex: a chemogenetic fMRS-BOLD study. NMR Biomed. 2016 Dec;29(12):1678-1687. PMID: 27696530; PMCID: PMC5123928.
Guilfoyle DN, Gerum S, Vadasz C. In vivo Proton NMR spectroscopy of genetic mouse models BALB/cJ and C57BL/6By: variation in hippocampal glutamate level and the metabotropic glutamate receptor, subtype 7 (Grm7) gene. J Mol Neurosci. 2014 May;53(1):135-41. PMID: 24390354.
Kaur G, Sharma A, Xu W, Gerum S, Alldred MJ, Subbanna S, Basavarajappa BS, Pawlik M, Ohno M, Ginsberg SD, Wilson DA, Guilfoyle DN, Levy E. Glutamatergic transmission aberration: a major cause of behavioral deficits in a murine model of Down's syndrome. J Neurosci. 2014 Apr 9;34(15):5099-106. PMID: 24719089; PMCID: PMC3983795.
Guilfoyle DN, Gerum SV, Sanchez JL, Balla A, Sershen H, Javitt DC, Hoptman MJ. Functional connectivity fMRI in mouse brain at 7T using isoflurane. J Neurosci Methods. 2013 Apr 15;214(2):144-8. PMID: 23376497; PMCID: PMC3644382.