Dr. Lakatos attended medical school and studied neuroscience at the Semmelweis University in Budapest, Hungary. His area of focus was on characterizing attention related modulations of spontaneously occurring and stimulus driven gamma oscillations in auditory cortex using electrocorticographic recordings. Upon completion of his PhD, he joined the Nathan Kline Institute and began to investigate the mechanisms of neuronal oscillations on a more detailed spatial and temporal scale using laminar intracortical recordings. During the years he spent in Dr. Charles Schroeder’s lab, he described a hierarchy of low and high frequency oscillations (the Oscillatory Hierarchy) in sensory cortices, demonstrated multisensory interactions even at the level of primary cortical areas, determined that attention can regulate which of the senses controls excitability across all primary cortices, and described that rhythmic stimulation results in an entrainment of low frequency neuronal oscillations. Since becoming an independent investigator, his lab’s research established that topographically organized, counterphase entrained oscillations can be used as spectrotemporal filters in selective auditory attentional processes. Additionally, in collaboration with Dr. Daniel Javitt, the Lakatos lab has demonstrated that oscillatory entrainment is impaired in schizophrenia patients. Current studies are aimed at achieving two main goals: determining the role of internal rhythmic neuronal ensemble dynamics in the processing of external and internal information; and defining the top-down and bottom up circuitry that enables the dynamic modulation of this “neurophysiological context.”
Dr. Lakatos is also a Research Assistant Professor in the Department of Psychiatry at NYU Langone Medical Center.
Lakatos,P., Ankoor,S.S., Knuth,K.H., Ulbert,I., Karmos,G., and Schroeder,C.E. (2005). An Oscillatory Hierarchy Controlling Neuronal Excitability and Stimulus Processing in the Auditory Cortex. J. Neurophysiol. 94, 1904-1911.
Lakatos,P., Karmos, G., Mehta, A. D., Ulbert,I., and Schroeder, C. E. (2008) Entrainment of neuronal oscillations as a mechanism of attentional selection. Science 320, 110-113.
Lakatos, P., Musacchia G, O’Connel MN, Falchier AY, Javitt DC and Schroeder CE. (2013)."The spectrotemporal filter mechanism of auditory selective attention. Neuron 77(4): 750-61.
Lakatos, P., Schroeder CE, Leitman DI and Javit DC. (2013). Predictive suppression of cortical excitability and its deficit in schizophrenia. J Neurosci 33(28): 11692-702.
O’Connell,M.N., Barczak, A., Schroeder,C. and Lakatos,P. (2014). Layer specific sharpening of frequency tuning by selective attention in primary auditory cortex. J Neurosci 34(49):16496-508., 805-817.