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The Nathan S. Kline Institute for Psychiatric Research

Chris Goulbourne, Ph.D.

Chris Goulbourne, Ph.D.

Director of Electron Microscopy
Center for Dementia Research

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Dr. Chris Goulbourne obtained his B.Sc. from Durham University and Ph.D. from Oxford University in molecular cell biology. He then went on to do an American Heart Association postdoctoral fellowship at UCLA where he specialized in electron microscopy techniques such as ultrastructural analysis, electron tomography, immunogold electron microscopy, correlative light and electron microscopy, and Nano Secondary Ion Mass Spectrometry (NanoSIMS). Since his postdoctoral fellowship he has managed electron microscopy laboratories at GlaxoSmithKline and Columbia University and now directs the facility at the Nathan Kline Institute to support investigators’ research.

Select Publications

Jiang H, Goulbourne CN, Tatar A, Turlo K, Wu D, Beigneux AP, Grovenor CR, Fong LG, Young SG. High-resolution imaging of dietary lipids in cells and tissues by NanoSIMS analysis. J Lipid Res. 2014 Oct;55(10):2156-66.

Goulbourne CN, Gin P, Tatar A, Nobumori C, Hoenger A, Jiang H, Grovenor CR, Adeyo O, Esko JD, Goldberg IJ, Reue K, Tontonoz P, Bensadoun A, Beigneux AP, Young SG, Fong LG. The GPIHBP1-LPL complex is responsible for the margination of triglyceride-rich lipoproteins in capillaries. Cell Metab. 2014 May 6;19(5):849-60.

Jiang H, Favaro E, Goulbourne CN, Rakowska PD, Hughes GM, Ryadnov MG, Fong LG, Young SG, Ferguson DJ, Harris AL, Grovenor CR. Stable isotope imaging of biological samples with high resolution secondary ion mass spectrometry and complementary techniques. Methods. 2014 Jul 1;68(2):317-24.

Davies BS, Goulbourne CN, Barnes RH 2nd, Turlo KA, Gin P, Vaughan S, Vaux DJ, Bensadoun A, Beigneux AP, Fong LG, Young SG. Assessing mechanisms of GPIHBP1 and lipoprotein lipase movement across endothelial cells. J Lipid Res. 2012 Dec;53(12):2690-7.

Malhas A, Goulbourne C, Vaux DJ. The nucleoplasmic reticulum: form and function. Trends Cell Biol. 2011 Jun;21(6):362-73.